Cavitary Disease and Quantitative Sputum Bacillary Load in Cases of Pulmonary Tuberculosis

Author:

Palaci Moises1,Dietze Reynaldo1,Hadad David Jamil1,Ribeiro Fabiola Karla Corrêa1,Peres Renata Lyrio1,Vinhas Solange Alves1,Maciel Ethel Leonor Noia1,do Valle Dettoni Valdério1,Horter Libby2,Boom W. Henry2,Johnson John L.2,Eisenach Kathleen D.3

Affiliation:

1. Núcleo de Doenças Infecciosas, Centro de Ciências da Saúde, Universidade Federal do Espírito Santo, Vitória, Brazil

2. Department of Medicine, Division of Infectious Diseases, Case Western Reserve University School of Medicine and University Hospitals Case Medical Center, Cleveland, Ohio

3. Departments of Pathology and Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, Arkansas

Abstract

ABSTRACT We examined sputum bacterial loads in adults with newly diagnosed tuberculosis using quantitative culture and time-until-positive (DTP) culture in BACTEC 460. Patients with cavitary disease had higher CFU levels than those without cavities and shorter DTPs. Within radiographic strata of moderately and far advanced tuberculosis, higher CFU counts were associated with cavitary disease.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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