An Efficient, Clean, and Catalyst-Free Synthesis of Fused Pyrimidines Using Sonochemistry-Reference-Cited by-同舟云学术

An Efficient, Clean, and Catalyst-Free Synthesis of Fused Pyrimidines Using Sonochemistry

Published:2014-11-16 Issue: Volume:2014 Page:1-9
ISSN:2090-200X
Container-title:Organic Chemistry International
language:en
Short-container-title:Organic Chemistry International

Author:

Mamaghani M.¹,Tabatabaeian K.¹,Araghi R.¹,Fallah A.²,Hossein Nia R.¹

Affiliation:

1. Department of Chemistry, Faculty of Sciences, University of Guilan, P.O. Box 41335-1914, Rasht, Iran

2. Department of Chemistry, Faculty of Sciences, Islamic Azad University, Rasht Branch, P.O. Box 41335-3516, Rasht, Iran

Abstract

In this report, synthesis of indenopyrido[2,3-d]pyrimidine and pyrimido[4,5-b]quinoline derivatives was investigated via one-pot three-component reaction between 6-amino-2-(alkylthio)-pyrimidin-4(3H)one, 1,3-indanedione, or 1,3-cyclohexadione and arylaldehyde under ultrasonic irradiation in ethylene glycol as solvent at 65°C. In these reactions fused pyrimidine derivatives were synthesized with high to excellent yields (82–97%) and short reaction times (10–33 min).

Funder

University of Guilan

Publisher

Hindawi Limited

Subject

General Earth and Planetary Sciences,General Engineering,General Environmental Science

Link

http://downloads.hindawi.com/archive/2014/406869.pdf

Reference49 articles.

1. Unique chlorine effect in regioselective one-pot synthesis of 1-alkyl-/allyl-3-(o-chlorobenzyl) uracils: anti-HIV activity of selected uracil derivatives

2. 6-[2-(Phosphonomethoxy)alkoxy]pyrimidines with Antiviral Activity

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