6-[2-(Phosphonomethoxy)alkoxy]pyrimidines with Antiviral Activity-Reference-Cited by-同舟云学术

6-[2-(Phosphonomethoxy)alkoxy]pyrimidines with Antiviral Activity

Published:2002-03-27 Issue:9 Volume:45 Page:1918-1929
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Holý Antonín¹,Votruba Ivan¹,Masojídková Milena¹,Andrei Graciela¹,Snoeck Robert¹,Naesens Lieve¹,De Clercq Erik¹,Balzarini Jan¹

Affiliation:

1. Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Flemingovo nám. 2, CZ-166 10 Praha 6, Czech Republic, and Rega Institute for Medical Research, Katholieke Universiteit Leuven, Minderbroedersstraat 10, B-3000 Leuven, Belgium

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm011095y

Reference72 articles.

1. Reviews: (a) Holý, A. Phosphonylmethyl analogues of nucleotides and their derivatives: chemistry and biology.Nucleosides Nucleotides1987,6,147−155. (b) Holý A. Isopolar Phosphorus-Modified Nucleotide Analogues. InAdvances in Antiviral Drug Design; De Clercq, E., Ed.; JAI Press: Greenwich, CT, 1994; pp 179−232. (c) Freeman, S.; Gardiner, J.M. Acyclic nucleosides as antiviral compounds.Mol. Biotechnol.1996,5,125−137.

2. HPMPC (cidofovir), PMEA (adefovir) and Related Acyclic Nucleoside Phosphonate Analogues: A Review of their Pharmacology and Clinical Potential in the Treatment of Viral Infections

3. Synthesis and in vitro evaluation of a phosphonate prodrug: bis(pivaloyloxymethyl) 9-(2-phosphonylmethoxyethyl)adenine

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