Synthesis, Structure, and Antifungal Activities of 3-(Difluoromethyl)-Pyrazole-4-Carboxylic Oxime Ester Derivatives-Reference-Cited by-同舟云学术

Synthesis, Structure, and Antifungal Activities of 3-(Difluoromethyl)-Pyrazole-4-Carboxylic Oxime Ester Derivatives

Published:2022-08-28 Issue: Volume:2022 Page:1-8
ISSN:1098-1071
Container-title:Heteroatom Chemistry
language:en
Short-container-title:Heteroatom Chemistry

Author:

Wang Bin¹²,Chen Wei-Ting¹²,Min Li-Jing³,Han Liang¹,Sun Na-Bo²^ORCID,Liu Xing-Hai¹^ORCID

Affiliation:

1. College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014, China

2. College of Biology and Environmental Engineering, Zhejiang Shuren University, Hangzhou 310015, Zhejiang, China

3. College of Life Science, Key Laboratory of Vector Biology and Pathogen Control of Zhejiang Province, Huzhou University, Huzhou 313000, Zhejiang, China

Abstract

Fifteen new pyrazole-4-carboxylic oxime ester derivatives were conveniently synthesized, and their structures were confirmed by 1H NMR, 13C NMR, HRMS, and X-ray diffraction. Antifungal assays indicated that some of these compounds possessed good activity against S. sclerotiorum, B. cinerea, R. solani, P. oryae, and P. piricola at 50 ppm. Structure-activity relationships (SAR) were studied by molecular docking simulation.

Funder

Natural Science Foundation of Zhejiang Province

Publisher

Hindawi Limited

Subject

General Chemistry

Link

http://downloads.hindawi.com/journals/htrc/2022/6078017.pdf

Reference32 articles.

1. Synthesis and Pesticidal Activities of New Quinoxalines

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3. Synthesis, Crystal Structure, Herbicidal Activity, and SAR Study of Novel N-(Arylmethoxy)-2-chloronicotinamides Derived from Nicotinic Acid