Affiliation:
1. Lipoproteins and Atherosclerosis Research Laboratory, Faculty of Sciences Ben Msik, Casablanca, Morocco
2. Laboratory of Biochemistry, Faculty of Sciences Ain Chock, Casablanca, Morocco
3. Endocrinology and Nutrition, and Metabolic Diseases Department, University Hospital of Ibn Sina, Rabat, Morocco
Abstract
In this study, we investigate the effect of argan oil consumption on serum lipids, apolipoproteins (AI and B), CRP, and LDL susceptibility to oxidation in type 2 diabetic patients which are known to have a high level of cardiovascular risk due to lipid abnormalities and lipid peroxidation. For that, 86 type 2 diabetic patients with dyslipidemia were randomized to one group consuming 25 mL/day of argan oil during 3 weeks and control group consuming 20 g/day of butter in breakfast. After argan oil intervention, serum triglycerides decreased by 11.84%,(P=0.001), total chol by 9.13%,(P=0.01), and LDL-chol by 11.81%,(P=0.02). However, HDL-chol and Apo AI increased (10.51%,P=0.01and 9.40%, P=0.045,resp.). Susceptibility of LDL to lipid peroxidation was significantly reduced by increasing of 20.95%,(P=0.038)in lag phase after argan oil consumption. In conclusion, we show for the first time that consumption of argan oil may have an antiatherogenic effect by improving lipids, and the susceptibility of LDL to oxidation in type 2 diabetes patients with dyslipidemia, and can therefore be recommended in the nutritional management of type 2 diabetes.
Subject
Endocrine and Autonomic Systems,Endocrinology,Endocrinology, Diabetes and Metabolism
Cited by
11 articles.
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1. Beneficial Effects of Polyphenol-Rich Food Oils in Cardiovascular Health and Disease;Reviews in Cardiovascular Medicine;2023-07-03
2. The quality of cold-pressed edible argan oil available on the European market;Acta Poloniae Pharmaceutica - Drug Research;2022-06-18
3. Argan Yağı ve Biyolojik Aktivitelerinin Değerlendirilmesi;Mersin Üniversitesi Tıp Fakültesi Lokman Hekim Tıp Tarihi ve Folklorik Tıp Dergisi;2022-05-29
4. The Properties and Application of Argan Oil in Cosmetology;European Journal of Lipid Science and Technology;2019-02-25
5. Argan [Argania spinosa (L.) Skeels] Oil;Fruit Oils: Chemistry and Functionality;2019