Synthesis, Characterization, and Anti-Inflammatory Activity of Newer Quinazolinone Analogs-Reference-Cited by-同舟云学术

Synthesis, Characterization, and Anti-Inflammatory Activity of Newer Quinazolinone Analogs

Published:2013-01-17 Issue: Volume:2013 Page:1-7
ISSN:2090-9918
Container-title:Journal of Pharmaceutics
language:en
Short-container-title:Journal of Pharmaceutics

Author:

Rajput Chatrasal Singh¹²,Singhal Shiwani¹

Affiliation:

1. Medicinal Chemistry Division, Department of Pharmacology, L.L.R.M. Medical College, Meerut 250002, India

2. Jubilant Chemsys Ltd. R & D B-34, Sector 58, Noida 201301, India

Abstract

A series of 3-[2′-(Substitutedbenzylideneamino)phenyl]-2-methyl-6-substituted quinazolin-4-ones (5–10), 3-[2′-(3″-chloro-2″-oxo-4″-substitutedphenylazetidin-1″-yl)phenyl]-2-methyl-6-substitutedquinazolin-4-ones (11–16), and 3-[2′-(2″-substitutedphenyl-4″-oxo-1″,3″-thiazolidin-3″-yl)phentl]-2-methyl-6-substitutedquinazolin-4-ones (17–22) have been synthesized in the present study. The structures of the synthesized compounds were assigned on the basis of elemental analysis, IR, H1 NMR, and mass spectral data. All the newly synthesized compounds were screened for anti-inflammatory and analgesic activities.

Publisher

Hindawi Limited

Link

http://downloads.hindawi.com/archive/2013/907525.pdf

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