Structure–Activity Relationship and Molecular Docking of Quinazolinones Inhibiting Expression of COX-2, IL-1β, iNOS, and TNF-α through NF-κB Pathways-Reference-Cited by-同舟云学术

Structure–Activity Relationship and Molecular Docking of Quinazolinones Inhibiting Expression of COX-2, IL-1β, iNOS, and TNF-α through NF-κB Pathways

Published:2023-08-15 Issue:9 Volume:14 Page:1167-1173
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Kerdphon Sutthichat¹²^ORCID,Khamto Nopawit³⁴,Buddhachat Kittisak⁵,Ngoenkam Jatuporn⁶,Paensuwan Pussadee⁷,Pongcharoen Sutatip⁸,Singh Thishana⁹,Meepowpan Puttinan³¹⁰^ORCID,Jongcharoenkamol Jira¹¹^ORCID

Affiliation:

1. Department of Chemistry, Faculty of Science, Naresuan University, Phitsanulok 65000, Thailand

2. Center of Excellence in Petroleum, Petrochemicals and Advanced Materials, Faculty of Science, Naresuan University, Phitsanulok 65000, Thailand

3. Department of Chemistry, Faculty of Science, Chiang Mai University, Chiang Mai 50200, Thailand

4. Graduate School, Chiang Mai University, Chiang Mai 50200, Thailand

5. Department of Biology, Faculty of Science, Naresuan University, Phitsanulok 65000, Thailand

6. Department of Microbiology and Parasitology, Faculty of Medical Science, Naresuan University, Phitsanulok 65000, Thailand

7. Department of Optometry, Faculty of Allied Health Sciences, Naresuan University, Phitsanulok 65000, Thailand

8. Department of Medicine, Faculty of Medicine, Naresuan University, Phitsanulok 65000, Thailand

9. School of Chemistry and Physics, University of Kwazulu-Natal, Private Bag X54001, Durban 4000, South Africa

10. Center of Excellence in Material Science and Technology, Chiang Mai University, Chiang Mai 50200, Thailand

11. Department of Pharmaceutical Chemistry and Pharmacognosy, Faculty of Pharmaceutical Science, Naresuan University, Phitsanulok 65000, Thailand

Funder

Chiang Mai University

Naresuan University

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.3c00098

Reference18 articles.

1. The discovery and development of antiinflammatory drugs

2. Mechanism of action and potential applications of selective inhibition of microsomal prostaglandin E synthase-1-mediated PGE2 biosynthesis by sonlicromanol’s metabolite KH176m

3. Quinazolinone Analogs as Potential Therapeutic Agents

4. Synthesis and Biological Evaluation of Novel Bouchardatine Derivatives as Potential Adipogenesis/Lipogenesis Inhibitors for Antiobesity Treatment

5. Antimalarial Activities and Therapeutic Properties of Febrifugine Analogs

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