Natural Antioxidants: A Review of Studies on Human and Animal Coronavirus

Author:

Diniz Lúcio Ricardo Leite1,Bezerra Filho Carlos da Silva Maia2,Fielding Burtram C.3ORCID,de Sousa Damião Pergentino2ORCID

Affiliation:

1. College of Nordeste da Bahia, Coronel João Sá, Bahia, Brazil

2. Department of Pharmaceutical Sciences, Federal University of Paraíba, João Pessoa, PB, Brazil

3. Molecular Biology and Virology Research Laboratory, Department of Medical Biosciences, University of the Western Cape, Cape Town, South Africa

Abstract

The outbreaks of viruses with wide spread and mortality in the world population have motivated the research for new therapeutic approaches. There are several viruses that cause a biochemical imbalance in the infected cell resulting in oxidative stress. These effects may be associated with the development of pathologies and worsening of symptoms. Therefore, this review is aimed at discussing natural compounds with both antioxidant and antiviral activities, specifically against coronavirus infection, in an attempt to contribute to global researches for discovering effective therapeutic agents in the treatment of coronavirus infection and its severe clinical complications. The contribution of the possible action of these compounds on metabolic modulation associated with antiviral properties, in addition to other mechanisms of action, is presented.

Funder

University of the Western Cape

Publisher

Hindawi Limited

Subject

Cell Biology,Aging,General Medicine,Biochemistry

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