Alzheimers Disease-Like Neuropathology Following Exposure to Ambient Noise

Abstract

Many factors play a role in the risk of dementia, including the environment. Widespread and significant worldwide exposure to noise, the severity of related health consequences, and the limited tools available to the public to protect themselves strongly support the WHO's argument that 'noise pollution is not only an environmental nuisance but also a threat to public health'. Exposures to noise from industrial activities, airport noise, or occupational noise are very important. One of the limitations of such studies is the lack of information about lifestyle habits that can play a key role in a person's risk of dementia. This review suggests that people with more exposure to ambient noise are at higher risk of Alzheimer’s Disease (AD) and dementia than other people and we examined how chronic noise exposure causes neuropathology such as AD and how it relates to ApoE4 activation. Further studies are essential to expanding global knowledge about the harmful health effects and costs of health care due to noise pollution.