Highly Efficient, Reusable, Functionalized Pyridinium Salts as a Catalyst for the Simple and Cost-effective Preparation of Tetrahydro [b] Benzopyran Derivatives-Reference-Cited by-同舟云学术

Highly Efficient, Reusable, Functionalized Pyridinium Salts as a Catalyst for the Simple and Cost-effective Preparation of Tetrahydro [b] Benzopyran Derivatives

Published:2022-09 Issue:3 Volume:9 Page:252-261
ISSN:2213-3372
Container-title:Current Organocatalysis
language:en
Short-container-title:COCAT

Author:

Khiri-Meribout Naima¹^ORCID,Benzerka Saida¹,Redouane Mohamed Abdenour¹,Debache Abdelmadjid¹^ORCID

Affiliation:

1. Department of Chemistry, Faculty of Exact Sciences, University of Mentouri Brothers Constantine 1, Constantine, Algeria

Abstract

Background: In this work, a series of pyridinium-based ionic liquids (PBILs) were synthesized. Methods: Pyridinium-based ionic liquids (PBILs) were synthesized through a simple method, which was initially evaluated as catalysts for the synthesis of tetrahydro[b]benzopyran derivatives via a one-pot three-component reaction involving aldehydes, malononitrile, and dimedone. Results: The PBILs perform well in this condensation reaction, especially 1-methylpyridin-1-ium dimethyl phosphate (MPDMP). Conclusion: The advantages of this procedure are good yields, short reaction time, simplicity of implementation, and inexpensive starting materials.

Publisher

Bentham Science Publishers Ltd.

Subject

Organic Chemistry,Analytical Chemistry,Catalysis

Reference43 articles.

1. Ellis G.P.; Chromenes, chromanones, and chromones, The Chemistry of Heterocyclic Compounds Chromenes; Weissberger, A 1977,11-139

2. Hafez E.A.; Elnagd M.H.; Elagemey A.G.A.; El-Taweel F.M.A.A.; Nitriles in Heterocyclic Synthesis: Novel Synthesis of Benzo[c]coumarin and Benzo[c]pyrano[3,2-c]quinoline Derivatives. Heterocycles 1987,26,903-907

3. Khafagy M.M.; Abd El-Wahab A.H.; Eid F.A.; El-Agrody A.M.; Synthesis of halogen derivatives of benzo[h]chromene and benzo[a]anthracene with promising antimicrobial activities. Farmaco 2002,57(9),715-722

4. Smith P.W.; Sollis S.L.; Howes P.D.; Cherry P.C.; Starkey I.D.; Cobley K.N.; Weston H.; Scicinski J.; Merritt A.; Whittington A.; Wyatt P.; Taylor N.; Green D.; Bethell R.; Madar S.; Fenton R.J.; Morley P.J.; Pateman T.; Beresford A.; Dihydropyrancarboxamides related to zanamivir: A new series of inhibitors of influenza virus sialidases. 1. Discovery, synthesis, biological activity, and structure-activity relationships of 4-guanidino- and 4-amino-4H-pyran-6-carboxamides. J Med Chem 1998,41(6),787-797

5. Martinez A.G.; Marco L.; Friedländer reaction on 2-amino-3- cyano-4H-pyrans: Synthesis of derivatives of 4H-pyran [2, 3-b] quinoline, new tacrine analogs. J Bioorg Med Chem Lett 1997,7,3165-3170

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Efficient, Green One-Pot Synthesis of Antimicrobial Agents: Functionalized DPTS Catalyst for the Preparation of 2-Amino-4-Aryl-5-Oxo-4HChromene- 3-Carbonitriles, with Theoretical Calculations;Current Organocatalysis;2023-12

2. A Review on the Recent Progress of Layered Double Hydroxides (LDHs)- based Catalysts for Heterocyclic Synthesis;Current Organocatalysis;2023-10-27