Nanopolymers: powerful tools in neuroprotection and neuroregeneration

Author:

dos Santos Marcelo Garrido1,Prestes João Pedro1ORCID,Pranke Patricia1ORCID

Affiliation:

1. Hematology and Stem Cell Laboratory, Faculty of Pharmacy, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil

Abstract

: Disorders of the central and peripheral nervous systems are still major human health issues. Researchers have been seeking ways to boost neuroregeneration and neuroprotection since ancient times in order to overcome the brain's, spinal cord's, and peripheral nerves' limited ability to regenerate spontaneously.In this scenario, nanopolymers have shown great potential in terms of drug delivery systems and scaffolds, diminishing the scale of tissue damage and promoting functional recovery in both acute and chronic injuries. A diversity of natural and synthetic polymers has been exploited due to the unique characteristics of these polymers regarding their mechanical and biological properties. These properties dictate how the biomaterial interact with biological systems and how they are distinct in each polymer. This makes them suitable for numerous applications that range from the controlled release of an anti-inflammatory drug to axonal guidance. The versatility of nanopolymers makes them a rich source for therapeutic approaches in the neuroscience field, especially in neuroprotection and neuroregeneration.

Publisher

Bentham Science Publishers Ltd.

Subject

Pharmaceutical Science,Biomedical Engineering,Medicine (miscellaneous),Bioengineering,Biotechnology

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