Current Challenges and Implications of Proteogenomic Approaches in Prostate Cancer-Reference-Cited by-同舟云学术

Current Challenges and Implications of Proteogenomic Approaches in Prostate Cancer

Published:2020-10-08 Issue:22 Volume:20 Page:1968-1980
ISSN:1568-0266
Container-title:Current Topics in Medicinal Chemistry
language:en
Short-container-title:CTMC

Author:

Shukla Nidhi¹,Siva Narmadhaa¹,Malik Babita²,Suravajhala Prashanth¹^ORCID

Affiliation:

1. Department of Biotechnology and Bioinformatics, Birla Institute of Scientific Research, Statue Circle, Jaipur 302001, RJ, India

2. Department of Chemistry, School of Basic Sciences, Manipal University Jaipur, Jaipur, India

Abstract

In the recent past, next-generation sequencing (NGS) approaches have heralded the omics era. With NGS data burgeoning, there arose a need to disseminate the omic data better. Proteogenomics has been vividly used for characterising the functions of candidate genes and is applied in ascertaining various diseased phenotypes, including cancers. However, not much is known about the role and application of proteogenomics, especially Prostate Cancer (PCa). In this review, we outline the need for proteogenomic approaches, their applications and their role in PCa.

Publisher

Bentham Science Publishers Ltd.

Subject

Drug Discovery,General Medicine

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