Affiliation:
1. Department of Pharmaceutics,
Faculty of Pharmacy, University of Tabuk, Tabuk 71491, Saudi Arabia
2. Department of Pharmaceutics, Faculty of
Pharmacy, Sinai University, Alarish, North Sinai 45511, Egypt
3. Pharm D Program, Faculty of Pharmacy, University of Tabuk, Tabuk, Saudi Arabia
Abstract
Background:
Colloidal dispersions, also known as vesicular drug delivery systems
(VDDSs), are highly ordered assemblies composed of one or more concentric bilayers formed by the
self-assembly of amphiphilic building blocks in the presence of water.
Objectives:
VDDSs are important to target the entrapped drugs at specific sites inside the body, control
the drug release, enhance the drug bioavailability, and reduce undesired side effects.
Methods:
There are different types of VDDSs suitable for the entrapment of both hydrophilic and lipophilic
drugs. According to the composition, VDDSs are classified into lipid-based and non-lipid-based
VDDSs.
Results:
There are different types of VDDSs which include liposomes, ethosomes, transferosomes,
ufasomes, colloidosomes, cubosomes, niosomes, bilosomes, aquasomes, etc.
Conclusion:
This review article aims to address the different types of VDDSs, their advantages and
disadvantages, and their therapeutic applications.
Publisher
Bentham Science Publishers Ltd.
Subject
General Engineering,Condensed Matter Physics,General Materials Science
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