Affiliation:
1. Graduate Institute of Metabolism and Obesity Science, Taipei Medical University, Taipei City 11031, Taiwan
2. Ph.D. Program in Drug Discovery and Development Industry, College of Pharmacy, Taipei Medical University, Taipei City 11031, Taiwan
3. School of Nutrition and Health Sciences, Taipei Medical University, Taipei City 11031, Taiwan
Abstract
Metabolic syndrome is an aggregation of conditions and associated with an increased risk of developing
diabetes, obesity and cardiovascular diseases (CVD). Edible mushrooms are widely consumed in many countries
and are valuable components of the diet because of their attractive taste, aroma, and nutritional value. Medicinal
mushrooms are higher fungi with additional nutraceutical attributes having low-fat content and a transisomer
of unsaturated fatty acids along with high fiber content, biologically active compounds such as polysaccharides
or polysaccharide β-glucans, alkaloids, steroids, polyphenols and terpenoids. In vitro experiments, animal
models, and even human studies have demonstrated not only fresh edible mushroom but also mushroom
extract that has great therapeutic applications in human health as they possess many properties such as antiobesity,
cardioprotective and anti-diabetic effect. They are considered as the unmatched source of healthy foods
and drugs. The focus of this report was to provide a concise and complete review of the novel medicinal properties
of fresh or dry mushroom and extracts, fruiting body or mycelium and its extracts, fiber, polysaccharides,
beta-glucan, triterpenes, fucoidan, ergothioneine from edible mushrooms that may help to prevent or treat metabolic
syndrome and associated diseases.
Publisher
Bentham Science Publishers Ltd.
Subject
Drug Discovery,Pharmacology
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