Selenium Status in Elderly People: Longevity and Age-Related Diseases-Reference-Cited by-同舟云学术

Selenium Status in Elderly People: Longevity and Age-Related Diseases

Published:2019-08-19 Issue:15 Volume:25 Page:1694-1706
ISSN:1381-6128
Container-title:Current Pharmaceutical Design
language:en
Short-container-title:CPD

Author:

Robberecht Harry¹,De Bruyne Tess¹,Davioud-Charvet Elisabeth²,Mackrill John³,Hermans Nina¹

Affiliation:

1. Research Group NatuRA, Department of Pharmaceutical Sciences, Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, University of Antwerp, 2610 Antwerp, Belgium

2. Laboratoire d'Innovation Moleculaire et Application (LIMA), UMR7042 CNRSUnistra- UHA, European School of Chemistry, Polymers and Materials (ECPM), 25, rue Becquerel, F-67087 Strasbourg, France

3. Department of Physiology, School of Medicine, University College Cork, Western Gateway Building, Western Road, Cork, T12XF62, Ireland

Abstract

Background:Selenium (Se) is a trace element active in selenoproteins, which can regulate oxidative stress. It is generally perceived as an import factor for maintaining health in the elderly.Methods:The goal of this review is to discuss selenium concentration in biological samples, primarily serum or plasma, as a function of age and its relation with longevity. The elemental level in various age-related diseases is reviewed.Conclusion:Highest selenium values were observed in healthy adults, while in an elderly population significantly lower concentrations were reported. Variables responsible for contradictory findings are mentioned. Risk and benefits of Se-supplementation still remain under debate.

Funder

COST

Publisher

Bentham Science Publishers Ltd.

Subject

Drug Discovery,Pharmacology

Reference165 articles.

1. Rockenfeller P.; Madeo F.; Ageing and eating. Biochim Biophys Acta [http://dx.doi.org/10.1016/j.bbamcr.2010.01.001]. [PMID: 20079384].2010,1803(4),499-506

2. Hoffmann P.R.; Berry M.J.; The influence of selenium on immune responses. Mol Nutr Food Res [http://dx.doi.org/10.1002/mnfr.200700330]. [PMID: 18384097].2008,52(11),1273-1280

3. Mocchegiani E.; Malavolta M.; Muti E.; Zinc, metallothioneins and longevity: Interrelationships with niacin and selenium. Curr Pharm Des [http://dx.doi.org/10.2174/138161208786264188]. [PMID: 18991691].2008,14(26),2719-2732

4. Mocchegiani E.; Costarelli L.; Giacconi R.; Micronutrient-gene interactions related to inflammatory/immune response and antioxidant activity in ageing and inflammation. A systematic review. Mech Ageing Dev [http://dx.doi.org/10.1016/j.mad.2013.12.007]. [PMID: 24388876].2014,136-137,29-49

5. Brigelius-Flohé R.; The evolving versatility of selenium in biology. Antioxid Redox Signal [http://dx.doi.org/10.1089/ars.2015.6469]. [PMID: 26406357].2015,23(10),757-760

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