Potential of Gentiana lutea for the Treatment of Obesity-associated Diseases

Author:

Joksić Gordana1,Tričković Jelena Filipović1,Joksić Ivana1

Affiliation:

1. Vinca Institute of Nuclear Science, University of Belgrade, M.Petrovica Alasa 12-14, 11000 Belgrade, Serbia

Abstract

Background::Obesity, diabetes, and associated diseases are increasing all over the world, and pose a great burden on public health. According to the latest reports, 440 million people are suffering from diabetes. Diabetes is caused by impaired ability to produce or respond to the hormone insulin consequently resulting in hyperglycemia.Methods::Data used for this review was obtained by using PUBMED/MEDLINE (1987-2018). The main data search terms were: Gentiana lutea, Gentiana lutea extract, Gentiana lutea constituents, obesity, diabetes mellitus, diabetic complications.Results::In the present review, we describe the potential of root powder of yellow gentian (Gentiana lutea) for the prevention of obesity and diabetes including complications related to this disease.Conclusion::Reasonably effective, low-cost alternatives could fulfill an important role for a large part of the human population and could be of great value for the food market. Even a modest reduction of morbidity and mortality with respect to this disease translates into millions of lives saved.

Funder

Serbian Ministry of Education, Science and Technological development

Publisher

Bentham Science Publishers Ltd.

Subject

Drug Discovery,Pharmacology

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