Affiliation:
1. Department of Pharmaceutics, Laureate Institute of Pharmacy, Kathog, H.P, India
2. Amrapali Institute of Pharmacy, Haldwani, Uttrakhand, India
Abstract
From the past three to four decades, ecologists and scientists have exhaustively
studied the effect of increased artificial light pollution at night on the ecological
and physiological behavior of mammals. The Suprachiasmatic Nuclei (SCN) or master
clock in the brain of mammals including humans synchronizes the physiological functions
with the light: dark cycle. The prolongation of light period in the light: dark cycle
disrupts the circadian rhythm of mammals causing several negative or modified physiological
consequences. Changed physiological level of melatonin, an important endocrine
hormone, had been identified as an important factor causing different consequences
such as cancer, diabetes mellitus, metabolic disturbances, oxidative stress, and
depression. The presence of artificial light at night is the demand of the era but
thoughts must be given to the prevention of consequences due to artificial light pollution
and ‘how much is needed’. The review paper discusses the effect of artificial light
pollution on the biological clock of humans and associated negative physiological consequences.
Further, the paper also briefly discusses the economics of light pollution
and measures needed to prevent physiological disorders in humans.
Publisher
Bentham Science Publishers Ltd.
Subject
Pharmacology (medical),Complementary and alternative medicine,Pharmaceutical Science
Cited by
18 articles.
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