Affiliation:
1. Department of Chemical, Biological, Pharmaceutical and Environmental Chemistry, University of Messina, Messina, Italy
Abstract
Abstract:
Dihydrochalcones are a class of secondary metabolites, possessing several biological
properties such as antitumor, antioxidant, antibacterial, antidiabetic, estrogenic,
anti-inflammatory, antithrombotic, antiviral, neuroprotective, and immunomodulatory
properties; therefore, they are currently considered promising candidates in the drug discovery
process. This review intends to debate their pharmacological actions with particular
attention to their antitumor activity against a panel of cancer cell lines and to the description
of the inhibition mechanisms of cell proliferation such as the regulation of angiogenesis,
apoptosis, etc.
Publisher
Bentham Science Publishers Ltd.
Subject
Pharmacology,Molecular Medicine,Drug Discovery,Biochemistry,Organic Chemistry
Cited by
2 articles.
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