Affiliation:
1. Laboratory of Chemistry and Environmental Chemistry (LCCE), Department of Chemistry, Faculty of Matter Sciences,
Batna-1 University, Batna 05000, Algeria
2. Department of Pharmacy, Faculty of Medicine, University of Batna 2
Mustapha Benboulaid, Batna 05000, Algeria
3. Department of Organisms Biology, Faculty of Natural Sciences and
Life, University of Batna 2 Mustapha Benboulaid, Batna 05000, Algeria
Abstract
Abstract:
The genus Helianthemum from the Cistaceae family includes about 110 plants, which are
well known for their wide therapeutic uses and interesting pharmacological activities. To the best of
our knowledge, there are no previous comprehensive and critical reviews on the therapeutic applications,
chemical composition, and biological properties of this genus. In this context, the present paper
describes a systematic mini-review on the traditional use, phytochemical composition, and pharmacological
properties of species belonging to the genus Helianthemum. For this, more than 75 papers covering
the period from 1970 to 2022 were collected and analyzed to achieve this review. From 110 species
of the genus Helianthemum, only 22 species were studied. Helianthemum species are widely used
in folk medicine for the treatment of respiratory, hepatic, renal, psychiatric, and inflammatory diseases.
According to the collected information, species from this genus have several pharmacological
properties linked to their rich chemical composition, particularly in phenolic compounds and flavonoids.
In fact, Helianthemum plants have antioxidant, antimicrobial, anti-inflammatory, analgesic, antidiabetic,
insecticide, anticancer, antiulcer, larvicide, chemo, and hepatoprotective activities, justifying
their various uses in traditional medicine. Despite the intense use of Helianthemum species in traditional
human and veterinary medicine, few studies were conducted on the phytochemical composition
and pharmacological activities of the plants constituting this genus. In fact, until now, the emphasis
has only been on twenty-two species and the work carried out was not explanatory, especially for
certain species. So it will be interesting to broaden the spectrum of the tested biological activities, especially
for endemic species in order to understand the possible modes of action and to confirm the
toxicity of certain species.
Funder
Algerian Ministry of Higher Education and Scientific Research
Publisher
Bentham Science Publishers Ltd.
Reference92 articles.
1. Jamshidi-Kia F.; Lorigooini Z.; Amini-Khoei H.; Medicinal plants: Past history and future perspective. J Herbmed Pharmacol 2018,7(1),1-7
2. Shakya A.K.; Medicinal plants: Future source of new drugs. Int J Herb Med 2016,4(4),59-64
3. Mabberley DJ; The plant-book: A portable dictionary of the vascular plants.Mabberley Cambridge university press: New York, NY, 1997,858,10011-4211
4. Raynaud C.; Contribution to the study of certain species of the genus “Helianthemum” sect.” Helianthemum”: preliminary note. An Jardin Bot Mad 1984,41(2),303-311
5. Quézel P; Santa S.; New flora of Algeria and southern desert regions. Centre National de la recherche scientifique: Paris,France, 1962,1962-1170