Affiliation:
1. Department of Analytical Chemistry, Faculty of Pharmacy, Ankara University, 06560 Yenimahalle, Ankara, Turkey
Abstract
Background:
The molecular imprinting technique has been applied in many fields including
separation, artificial antibody mimics, catalysis, sensing studies, and drug delivery. The reasons for the
popularity of this technique among the researchers are high selectivity due to the cavities that are
formed on the polymer surface for the specific analyte, high robustness, high durability under extreme
conditions and low cost. When these advantages are combined with the advantages of electrochemical
methods such as rapid response time, ease of use, cheapness and miniaturizability, Molecularly Imprinted
Polymer (MIP) based electrochemical sensors turn out to be a widely-preferred sensing tool.
Objective:
This article provides the reader with information on MIP-based electrochemical sensors and
reviews the applications of the MIP sensors prepared by electropolymerization of orthophenylenediamine,
a monomer whose mechanical and chemical stability is very high.
Results and Conclusion:
The literature survey summarized in this review shows that cyclic voltammetry
is the most widely preferred electrochemical technique for electropolymerization of o-PD. The media
chosen is generally acetate or phosphate buffers with different pH values. Although there are numerous
solvents used for template removal, generally methanol and NaOH have been chosen.
Publisher
Bentham Science Publishers Ltd.
Subject
Pharmaceutical Science,Molecular Medicine,Biochemistry,Biophysics
Cited by
25 articles.
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