Affiliation:
1. TÜRK-ALMAN ÜNİVERSİTESİ, FEN FAKÜLTESİ
2. ANKARA ÜNİVERSİTESİ, ECZACILIK FAKÜLTESİ, ANALİTİK KİMYA (DR)
Abstract
Objective: In this study, it was aimed to develop a voltammetric method using sensors prepared with the molecular imprinting technique for the detection of Captopril, an antihypertensive drug.
Material and Method: With the molecular imprinting method, molecularly imprinted polymers were formed on the surfaces of glassy carbon electrodes. The analysis of Captopril was carried out using the differential pulse voltammetry method, and the performance of the sensor was examined.
Result and Discussion: A linear analysis was performed up to 50 pM Captopril with a limit of detection value of 2.62 pM. Selectivity studies have shown that Captopril has a higher electrochemical response than other interfering substances, such as paracetamol, ascorbic acid, and L-proline.
Publisher
Ankara Universitesi Eczacilik Fakultesi Dergisi
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