Affiliation:
1. Faculty, Department of Pharmaceutical Sciences, Chandigarh Group of Colleges (CGC), Landran, Sahibzada Ajit Singh Nagar, India
2. Faculty, Department of Pharmaceutical Sciences, Panipat Institute of Engineering & Technology (PIET), Samalkha, Haryana 132102, India
Abstract
Abstract:P-coumaric acid is a common dietary polyphenol present in fruits, vegetables, and cereals in conjugated and free form. The toxicity profile of the drug is very low, and it exhibits many pharmacological actions (antihypertensive, anti-inflammatory, anticancer, antimicrobial activity, antidiabetic, anticancer, and antioxidant effect). P-coumaric acid also acts as a free radical scavenger and inhibits various enzymes, which generate free radicals. It is also used as the raw material for the preparation of preservatives, vanillin, sports foods, skin defense agents, and as a cross-linker for the formation of edible films and food gels. The current study is based upon biological effectiveness, molecular docking, SAR, sources of p-coumaric acid, and related derivatives.
Publisher
Bentham Science Publishers Ltd.
Subject
Drug Discovery,General Medicine
Cited by
5 articles.
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