A Novel One-pot Protocol for the Cu-Catalyzed Synthesis of Nine 2-Aminobenzimidazole Derivatives from o-Phenylenediamine and Trichloroacetonitrile-Reference-Cited by-同舟云学术

A Novel One-pot Protocol for the Cu-Catalyzed Synthesis of Nine 2-Aminobenzimidazole Derivatives from o-Phenylenediamine and Trichloroacetonitrile

Published:2019-01-09 Issue:2 Volume:16 Page:99-103
ISSN:1570-1786
Container-title:Letters in Organic Chemistry
language:en
Short-container-title:LOC

Author:

Nematpour Manijeh¹,Abedi Elham²,Abedi Elahe³

Affiliation:

1. Young Researchers and Elites Club, Science and Research Branch, Islamic Azad University, Tehran, Iran

2. Pathology Department, Shiraz University of Medical Siences, Shiraz, Iran

3. Department of Food Sciences and Technology, Fasa University, Fasa, Iran

Abstract

The synthesis of a variety of 2-aminobenzimidazoles via a one pot reaction of ophenylenediamine and trichloroacetonitrile catalyzed by copper (II) acetate in THF at room temperature, with good yields is described. Use of simple and readily available starting materials, good to high yields, free ligand, and no column chromatography are important features of this protocol.

Publisher

Bentham Science Publishers Ltd.

Subject

Organic Chemistry,Biochemistry

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