Affiliation:
1. Natural Products Research Lab, Department of Pharmaceutical Sciences, University of Kashmir, Jammu & Kashmir, 190006, India
Abstract
Around 3000 species of Saussurea are known, however Saussurea lappa Clarke
which is perennial herb and has been traditionally used as anticancer, anti-inflammatory,
antiviral, medicine without many adverse effects. Phytochemistry of Saussurea lappa after
thorough literature survey revealed various varied and copious metabolites such as sesquiterpenes,
flavonoids, phytosterols, lignans, terpenes. Many of these compounds have been
found to possess a wide range of biological activity such as anticancer, anti-inflammatory,
anti-hepatotoxic, anti-viral, etc. Among sesquiterpenes particularly Dehydrocostuslactone,
dihydrocostunolide, costunolide Lappadilactone, have been isolated as the main chemical
constituents. This review aims to cover published work from public databases (e.g. PubMed,
Google Scholar, ResearchGate) and Non-English, Ph.D./MS thesis databases (e.g. CKNIChina,
Jairo-Japan, Myto-Malaysia, Shodhganga-India) with a particular focus on
phytochemistry and therapeutic uses of different fractions as well as isolated compounds
from Saussurea lappa.
Publisher
Bentham Science Publishers Ltd.
Subject
Complementary and alternative medicine,Drug Discovery
Cited by
25 articles.
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