Affiliation:
1. Shobhaben Pratapbhai Patel School of Pharmacy and Technology Management, SVKM's Narsee Monjee Institute of
Management Studies (NMIMS), V.L. Mehta Road, Vile Parle (W), Mumbai 400 056, India
Abstract
Abstract:
Flavonoids have been reported to be vital in treating various chronic disorders. Luteolin
(3′,4′,5,7-tetrahydroxyflavone) is a flavonoid present in a variety of plant sources such as celery,
green pepper, olive oil, peppermint, thyme, rosemary, oregano, etc. It has been reported to
have various pharmacological activities such as antioxidant, anti-inflammatory, anticancer, antidiabetic,
anti-Alzheimer, antimicrobial, etc. Many scientific studies have been carried out on luteolin
for its possible effects on diabetes and its associated complications. The present review
focuses on the role of luteolin in diabetes mellitus and the associated complications. The antidiabetic
impact of luteolin is linked with the increased expression of PPARγ and GLUT. Various
in vitro and in vivo studies have been performed to explore the effects of luteolin on diabetic
complications, and it has shown a significant impact in the management of the same.
Publisher
Bentham Science Publishers Ltd.
Cited by
1 articles.
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