Affiliation:
1. Drug Design Laboratory, Faculty of Pharmacy, IFTM University, Moradabad, 244001, India
Abstract
Benzothiazole is a heterocyclic aromatic and bicyclic compound in which, benzene ring is
attached with thiazole ring. This nucleus is established in marine as well as terrestrial natural compounds.
The benzothiazole skeleton is established in a broad variety of bioactive heterocycles and
natural products. The benzothiazole nucleus is considered as the principle moiety in several biologically
active compounds. Over the decade, chemists are paying more attention towards the revision of
the biological and therapeutic activities such as antimicrobial, analgesic, antiinflammatory, antitubercular,
antiviral and antioxidant of benzothiazole containing compounds. The molecular structures of a
number of potent drugs including Frentizole, Pramipexole, Thioflavin T and Riluzole etc., are based
on benzothiazole skeleton. The present work is the compilation and presentation of all available information
in a systematic manner with an aim to present the findings in a way, which may be beneficial
for future research.
Publisher
Bentham Science Publishers Ltd.
Subject
Drug Discovery,Pharmacology,General Medicine
Cited by
31 articles.
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