Affiliation:
1. Department of Pharmacy, University of Science and Technology Chittagong, Chattogram, Bangladesh
2. Molecular Modeling Drug-design and Discovery Laboratory, Pharmacology Research Division, BCSIR Laboratories Chattogram, Bangladesh Council of Scientific and Industrial Research, Chattogram, Bangladesh
Abstract
Background:
Brassica oleracea var. capitata f. alba (white cabbage) is a cruciferous vegetable
used as a vegetable and traditional medicine all over the world. Different preparation from several
parts of the plant- roots, shoots, leaves, and the whole plant are used to treat a wide range of diseases,
including diabetes, cancer, gastric, inflammation, hypertension, hypercholesterolemia, bacterial,
oxidation, and obesity.
Objective:
The aim of the current review is to evaluate the botany, distribution, traditional uses, phytochemistry,
and pharmacological activities of B. oleracea var. capitata. Moreover, this review will
guide to fill the existing gaps in information and highlight additional research prospects in the field of
phytochemistry and pharmacology.
Method:
Various resources, including research papers, review papers, books, and reports, were collected
to obtain overall information on Brassica oleracea var. capitata, which were obtained by an
online search of worldwide-accepted scientific databases. Phytochemical constituents’ structures were
drawn by ChemDraw software.
Results:
About 72 isolated phytochemical compounds of B. oleracea var. capitata have been collected
from different articles, which included different types of compounds such as alkaloids, flavonoids,
organic acids, glucosinolates, steroids, hydrocarbons, etc. Crude extracts and phytoconstituents of B.
oleracea var. capitata have various pharmacological effects, including antidiabetic, anticancer, antihypertensive,
anticholesterolemic, antioxidant, anti-inflammatory, antibacterial, anti-obesity, anticoagulant,
and hepatoprotective. We have enlisted all these pharmacological data along with all the phytochemical
constituents of Brassica oleracea var. capitata.
Conclusion:
The study was focused on the traditional uses, pharmacological activities, and phytochemistry
of Brassica oleracea var. capitata, and the findings indicated that B. oleracea var. capitata
is an important medicinal plant that shows several pharmacological effects. We hope our review of
this plant will provide more basic and useful information and fill some research gaps for further investigation
and drug design. Although we found some important traditional uses and pharmacological
activities of Brassica oleracea var. capitata, there is insufficient work in the field of phytochemical
activities.
Publisher
Bentham Science Publishers Ltd.
Subject
Drug Discovery,Pharmacology,General Medicine