Current Development on Chitosan-based Antimicrobial Drug Formulations for the Wound Healing

Abstract

Background:: Derived from polyose, chitosan is an outstanding natural linear polysaccharide comprised of random arrangement of β-(1-4)-linked D-Glucosamine and N-acetyl-DGlucosamine units. Objective: Researchers have been using chitosan as a network forming or gelling agent with economically available, present polyose, low immunogenicity, biocompatibility, non-toxicity, biodegradability, protects against secretion from irritation and don’t suffer the danger of transmission animal infective agent. Methods: Furthermore, recent studies gear up the chitosan used in the development of various biopharmaceutical formulations, including nanoparticles, hydrogels, implants, films, fibers, etc. Results: These formulations produce potential activities as antimicrobials, cancer treatment, medical aid, and wound healing, controlled unleash device or drug trigger retarding device and 3DBiomedical sponge, etc. Conclusion: The present article discusses the development of various drug formulations utilizing chitosan as biopolymers for the repairing of broken tissues and healing in case of wound infection.