An Overview of Nanoformulated Nutraceuticals and their Therapeutic Approaches

Abstract

Background: Economic development and vast changes in food habits have accelerated the consumption of junk foods, which are the leading causes of several disorders that turn the majority of the people to use various herbal formulations or drugs for preventing various lifestyle diseases. Nutraceuticals are the borderline apparatus between nutrients and drugs that provide supplementation of the particular nutrient with a favorable health effect. Objective: Various nutraceutical compounds like vitamins, spices, polyphenols, prebiotics, and probiotics in the form of powders, tablets, and capsules are currently marketed globally. Among them, previous literature have reported that polyphenols are the most promising compounds that have been proven to treat various chronic diseases like cancer, hypertension, diabetes mellitus (DM), osteoporosis, osteoarthritis, dyslipidemia, multiple sclerosis, congenital anomalies, Alzheimer’s disease, etc. It is warranted to discuss the benefits of nanoformulations of nutraceuticals. Methods: We have searched PubMed using the keywords nutraceuticals, nanoformulations, therapeutic approaches, bionanotechnology, and therapeutics. The relevant papers and classical papers in this field were selected to write this review. Results and Discussion: The different classifications of nutraceuticals were described in this review. The comparison between the different categories of nutraceuticals with their nanoformulated forms was made, explaining the benefits of nanoformulations regarding stability, bioavailability, enhanced anti-oxidant properties, etc. A glimpse of the drawbacks of nanoformulations was also included. Conclusion: The current review highlights an overview of various nanoformulated nutraceuticals and their approach towards the treatment of multiple diseases.