Author:
Chopra Bhawna,Dhingra Ashwani Kumar,Kapoor Ram Prakash,Prasad Deo Nandan
Abstract
Piper nigrumL. is examined as the king of species worldwide by virtue of its principle piperine. In Ayurveda, since from the ancient times, it is known as “Yogvahi”. It is one of the important alkaloids of Pepper fruits (Family Piperaceae) and has been found to have numerous medicinal properties such as antioxidant, antiplatelet, anti-inflammatory, antihypertensive, hepatoprotective, antithyroid, antitumor, antiasthmatic activity and also have significant role as fertility enhancer. The present review discusses the biosynthetic pathway, extraction process, chemistry and various analytical methods of piperine. It also describes the structural modification of piperine and its various effects on biological system. The utility of piperine as a bioenhancer for certain antibacterial- antibiotics and a potent inhibitor of drug metabolism are also discussed. Thus, review provides knowledgeable erudition on the piperine which paves way for further work.
Publisher
Bentham Science Publishers Ltd.
Reference192 articles.
1. Singh YN. Kava: an overview. J Ethnopharmacol 1992; 37 (1) : 13-45.
2. Kirtikar KR, Basu B. Indian Medicinal Plants. 2nd ed. Dehradun 1995.
3. Li X, Yuan H, Gou K, Liu Z, Zhang C. Study of piperine in Fructus piperis Longi by supercritical fluid extraction. Zhongguo Yiyuan Zazhi 2000; 20 (10) : 597-9.
4. Ahmed M, Rahman MW, Rahman MT, Hossain CF. Analgesic principle from the bark of Careya arborea. Pharmazie 2002; 57 (10) : 698-701.
5. Warrier PK. The importance of black pepper in Ayurveda. Indian Spices 1981; 18 (2-4) : 3-5.
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