Affiliation:
1. Institute of Pharmaceutical Research, GLA University Mathura, U.P, 281406, India
2. Amity Institute of Management,
Rajarhat, Kolkata, West Bengal, 700160, India
Abstract
Abstract:
Piperine, an alkaloid from black pepper, has demonstrated diverse pharmacological properties
and potential therapeutic applications. Piperine content varies with the pepper plant and ranges
from 2 to 7.4% in black pepper. Piperine possesses remarkable biological properties, including antioxidant,
anti-inflammatory, antibacterial, anticancer, neuroprotective, and hepatoprotective qualities.
Its ability to affect numerous signaling pathways and biological targets implicated in disease development
is responsible for these functions. Studies have shown piperine to have high antioxidant activity,
which aids in reducing oxidative stress and preventing cellular damage. It has been established
that its anti-inflammatory effects suppress the generation of pro-inflammatory mediators, thereby
relieving inflammation-related diseases. This review emphasizes and examines piperine's medical
and health-promoting benefits and proposed mechanisms of action in health promotion and illness
prevention.
Publisher
Bentham Science Publishers Ltd.
Subject
Organic Chemistry,Biochemistry
Cited by
3 articles.
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