The effect of carboxylates of food acids and substances of neurotropicmetabolic effect on biochemical indicators of blood and reproductive qualities of new-calved cows

Abstract

After calving, changes occur in the reproductive system of cows, aimed at restoring the ability to reproduce. These processes occur against the background of exhaustion from childbirth, lactation, and a negative energy balance, which often leads to violations of the reproductive function, so the search for methods that contribute to its restoration is urgent. The aim of the work was to investigate the effect of the drug with nerotropic-metabolic action as a stimulator of postpartum recovery in cows and improvement of fertility. The drug included L-arginine, sodium succinate, sodium glutamate and carboxylates of food acids (Fe, Ca, Mn, Cu, Zn). The study was conducted by the method of groups on cows of the Holstein breed. A control and two experimental groups of 15 heads each were formed. Cows of experimental group 1 were given injections in the subcaudal fold on the 5th, 7th and 9th day after calving, dividing the active substance into 3 parts. Cows of experimental group 2 were administered the drug intraparenterally in the first 1.5-2 hours after calving in a full dose once 21st days after calving, the cows of the experimental groups did not show any deviations in blood biochemical parameters compared to the reference values. But there was a tendency to decrease the amount of calcium, phosphorus, protein and carotene, compared to cows of the control group, which indicates the presence of an influence on metabolic processes. The content of total protein in the blood of cows of experimental group 2 was close to the lower limit of the physiological norm. No placental retention was observed in the cows of the experimental groups, while in the control group this disorder was present in 33% of cows. The introduction of the drug made it possible to reduce the frequency of endometritis by 20%, to shorten the period until the beginning of the first oestrus by 7th and 10th days, to increase fertility after the first insemination by 6 and 13 percentage points, and to shorten the service period by 16th and 22nd days. The second experimental group obtained a higher efficiency of using the drug. It is advisable to use the results of research on dairy farms. Intraparenteral administration of the drug 1.5-2 hours after calving will improve the process of restoring the sexual function of cows and their fertility