Choriocarcinoma of the ovaries: the role of molecular-genetic testing in the differential diagnosis of gestational and non-gestational forms-Reference-Cited by-同舟云学术

Choriocarcinoma of the ovaries: the role of molecular-genetic testing in the differential diagnosis of gestational and non-gestational forms

Published:2024-07-15 Issue: Volume: Page:
ISSN:2587-6813
Container-title:Malignant tumours
language:
Short-container-title:Malignant Tumours

Author:

Letuchikh A. N.¹^ORCID,Ablyametova A. S.¹^ORCID,Zorinova A. V.¹^ORCID,Israelyan E. R.²^ORCID,Tsareva A. S.²^ORCID,Rumyantsev A. A.²^ORCID

Affiliation:

1. N. N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia; N. I. Pirogov Russian National Research Medical University, Ministry of Health of Russia

2. N. N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia

Abstract

The treatment approach for gestational and non-gestational ovarian choriocarcinoma has several differences, and their differential diagnosis requires special attention. The implementation of molecular-genetic testing which determines the presence of paternal genetic material in the tumor allows for a reliable determination of the origin of ovarian choriocarcinoma. The presented clinical case demonstrates the importance of this method in the differential diagnosis of gestational and non-gestational forms of ovarian choriocarcinoma.

Publisher

Russian Society of Clinical Oncology

Reference23 articles.

1. Bishop B.N., Edemekong P.F. Choriocarcinoma. In: StatPearls. Treasure Island (FL): StatPearls Publishing; February 4, 2023. PMID: 30571055

2. Liu X., Zhang X., Pang Y., et al. Clinicopathological factors and prognosis analysis of 39 cases of non-gestational ovarian choriocarcinoma. Arch Gynecol Obstet 2020;301(4):901–912. https://doi.org/10.1007/s00404-020-05502-9

3. Hayashi S., Abe Y., Tomita S., et al. Primary non-gestational pure choriocarcinoma arising in the ovary: A case report and literature review. Oncol Lett 2015;9(5):2109–2111. https://doi.org/10.3892/ol.2015.2985

4. Vance R.P., Geisinger K.R. Pure nongestational choriocarcinoma of the ovary. Report of a case. Cancer 1985;56(9):2321– 2325. https://doi.org/10.1002/1097-0142(19851101)56:9<2321::aid-cncr2820560931>3.0.co;2-q

5. Exman P., Takahashi T.K., Gattas G.F., et al. Primary ovary choriocarcinoma: individual DNA polymorphic analysis as a strategy to confirm diagnosis and treatment. Rare Tumors 2013;5(2):89–92. https://doi.org/10.4081/rt.2013.e24