Carnosine and anserine homeostasis in skeletal muscle and heart is controlled by β-alanine transamination

Author:

Blancquaert Laura1,Baba Shahid P.2,Kwiatkowski Sebastian3,Stautemas Jan1,Stegen Sanne1,Barbaresi Silvia1,Chung Weiliang1,Boakye Adjoa A.2,Hoetker J. David2,Bhatnagar Aruni2,Delanghe Joris4,Vanheel Bert5,Veiga-da-Cunha Maria3,Derave Wim1,Everaert Inge1

Affiliation:

1. Department of Movement and Sports Sciences; Ghent University; Ghent Belgium

2. Diabetes and Obesity Center; Department of Medicine; University of Louisville; Louisville KT USA

3. Laboratory of Physiological Chemistry; de Duve Institute; Université Catholique de Louvain; Brussels Belgium

4. Department of Clinical Chemistry; Ghent University Hospital; Ghent Belgium

5. Department of Basic Medical Sciences; Division of Physiology; Ghent University; Ghent Belgium

Funder

National Institutes of Health

Research Foundation - Flanders

Publisher

Wiley

Subject

Physiology

Reference41 articles.

1. Effects of traditionally used anxiolytic botanicals on enzymes of the gamma-aminobutyric acid (GABA) system;Awad;Can J Physiol Pharmacol,2007

2. Role of aldose reductase in the metabolism and detoxification of carnosine-acrolein conjugates;Baba;J Biol Chem,2013

3. Carnosine loading and washout in human skeletal muscles;Baguet;J Appl Physiol,2009

4. Elevation of y-aminobutyric acid in brain: selective inhibition of y-aminobutyric-a-ketoglutaric acid transaminase;Baxter;J Biol Chem,1961

5. Beta-alanine supplementation, muscle carnosine and exercise performance;Blancquaert;Curr Opin Clin Nutr Metab Care,2015

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