Impact of the F508del mutation on ovine CFTR, a Cl−channel with enhanced conductance and ATP-dependent gating-Reference-Cited by-同舟云学术

Impact of the F508del mutation on ovine CFTR, a Cl−channel with enhanced conductance and ATP-dependent gating

Published:2015-04-09 Issue:11 Volume:593 Page:2427-2446
ISSN:0022-3751
Container-title:The Journal of Physiology
language:en
Short-container-title:J Physiol

Author:

Cai Zhiwei¹,Palmai-Pallag Timea²³,Khuituan Pissared¹⁴,Mutolo Michael J.²,Boinot Clément⁵,Liu Beihui¹,Scott-Ward Toby S.¹,Callebaut Isabelle⁶,Harris Ann²,Sheppard David N.¹

Affiliation:

1. School of Physiology and Pharmacology; University of Bristol; Medical Sciences Building, University Walk Bristol BS8 1TD UK

2. Human Molecular Genetics Program; Lurie Children's Research Center and Department of Pediatrics; Northwestern University Feinberg School of Medicine; Chicago IL 60614 USA

3. Harris Laboratory; formerly at the Weatherall Institute of Molecular Medicine; University of Oxford; Oxford UK

4. Center of Calcium and Bone Research; Department of Physiology; Faculty of Science; Mahidol University; Bangkok 10400 Thailand

5. Institut de Physiologie et Biologie Cellulaires; Université de Poitiers; CNRS FRE 3511 86022 Poitiers France

6. IMPMC; Sorbonne Universités - UPMC Univ Paris 06; UMR CNRS 7590; Museum National d'Histoire Naturelle; IRD UMR 206 IUC 75005 Paris France

Funder

Cystic Fibrosis Foundation

Cystic Fibrosis Trust

French Cystic Fibrosis Association Vaincre la Mucoviscidose

National Institutes of Health

Publisher

Wiley

Subject

Physiology

Reference75 articles.

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2. Allosteric modulation balances thermodynamic stability and restores function of ΔF508 CFTR;Aleksandrov;J Mol Biol,2012

3. Voltage-dependent gating of the cystic fibrosis transmembrane conductance regulator Cl− channel;Cai;J Gen Physiol,2003

4. Phloxine B interacts with the cystic fibrosis transmembrane conductance regulator at multiple sites to modulate channel activity;Cai;J Biol Chem,2002

5. Differential sensitivity of the cystic fibrosis (CF)-associated mutants G551D and G1349D to potentiators of the cystic fibrosis transmembrane conductance regulator (CFTR) Cl− channel;Cai;J Biol Chem,2006

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