PTEN Regulates Glutamine Flux to Pyrimidine Synthesis and Sensitivity to Dihydroorotate Dehydrogenase Inhibition-Reference-Cited by-同舟云学术

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PTEN Regulates Glutamine Flux to Pyrimidine Synthesis and Sensitivity to Dihydroorotate Dehydrogenase Inhibition

Published:2017-03-02 Issue:4 Volume:7 Page:380-390
ISSN:2159-8274
Container-title:Cancer Discovery
language:en
Short-container-title:Cancer Discov

Author:

Mathur Deepti,Stratikopoulos Elias,Ozturk Sait,Steinbach Nicole,Pegno Sarah,Schoenfeld Sarah,Yong Raymund,Murty Vundavalli V.,Asara John M.,Cantley Lewis C.,Parsons Ramon

Funder

NIH

Breast Cancer Research Foundation

Publisher

American Association for Cancer Research (AACR)

Subject

Oncology

Cited by 104 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Identification of isoquinolinone DHODH inhibitor isosteres;Bioorganic & Medicinal Chemistry Letters;2024-09

2. A Patent Review of Human Dihydroorotate Dehydrogenase (hDHODH) Inhibitors as Anticancer Agents and their Other Therapeutic Applications (1999-2022);Recent Patents on Anti-Cancer Drug Discovery;2024-08

3. Coordinated Targeting of S6K1/2 and AXL Disrupts Pyrimidine Biosynthesis in PTEN-Deficient Glioblastoma;Cancer Research Communications;2024-08-01

4. DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation;eLife;2024-07-08

5. Discovery of JNJ-74856665: A Novel Isoquinolinone DHODH Inhibitor for the Treatment of AML;Journal of Medicinal Chemistry;2024-06-18

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