The Combi-Targeting Concept: In vitro and In vivo Fragmentation of a Stable Combi-Nitrosourea Engineered to Interact with the Epidermal Growth Factor Receptor while Remaining DNA Reactive-Reference-Cited by-同舟云学术

The Combi-Targeting Concept: In vitro and In vivo Fragmentation of a Stable Combi-Nitrosourea Engineered to Interact with the Epidermal Growth Factor Receptor while Remaining DNA Reactive

Published:2007-01-01 Issue:1 Volume:13 Page:331-340
ISSN:1078-0432
Container-title:Clinical Cancer Research
language:en
Short-container-title:Clin Cancer Res

Author:

Qiu Qiyu,Domarkas Juozas,Banerjee Ranjita,Merayo Nuria,Brahimi Fouad,McNamee James P.,Gibbs Bernard F.,Jean-Claude Bertrand J.

Publisher

American Association for Cancer Research (AACR)

Subject

Cancer Research,Oncology

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1. A multi-functional hypoxia/esterase dual stimulus responsive and hyaluronic acid-based nanomicelle for targeting delivery of chloroethylnitrosouea;Journal of Nanobiotechnology;2023-08-23

2. Molecular Analysis of the Superior Efficacy of a Dual Epidermal Growth Factor Receptor (EGFR)-DNA-Targeting Combi-Molecule in Comparison with Its Putative Prodrugs 6-Mono-Alkylamino- and 6,6-Dialkylaminoquinazoline in a Human Osteosarcoma Xenograft Model;Cells;2023-03-16

3. Development of Dual Inhibitors Targeting Epidermal Growth Factor Receptor in Cancer Therapy;Journal of Medicinal Chemistry;2022-03-21

4. Development and biological evaluation of AzoBGNU: A novel hypoxia-activated DNA crosslinking prodrug with AGT-inhibitory activity;Biomedicine & Pharmacotherapy;2021-12

5. NBGNU: a hypoxia-activated tripartite combi-nitrosourea prodrug overcoming AGT-mediated chemoresistance;Future Medicinal Chemistry;2019-02