Role of oxidative stress in the chemical structure-related genotoxicity of nitrofurantoin in Nrf2-deficient gpt delta mice

Author:

Tsuchiya Takuma12,Kijima Aki1,Ishii Yuji1,Takasu Shinji1,Yokoo Yuh1,Nishikawa Akiyoshi1,Yanai Tokuma2,Umemura Takashi13

Affiliation:

1. Division of Pathology, National Institute of Health Sciences, 3-25-26 Tonomachi, Kawasaki-ku, Kawasaki-shi, Kanagawa 210-9501, Japan

2. Pathogenetic Veterinary Science, United Graduate School of Veterinary Sciences, Gifu University, 1-1 Yanagido, Gifu-shi, Gifu 501-1193, Japan

3. Department of Animal Nursing, Yamazaki Gakuen University, 4-7-2 Minamiosawa, Hachioji-shi, Tokyo 192-0364, Japan

Publisher

Japanese Society of Toxicologic Pathology

Subject

Toxicology,Pathology and Forensic Medicine

Reference32 articles.

1. 1. IARC Working Group on the Evaluation of the Carcinogenic Risk to Humans Furaltadone. In: IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, vol. 7, International Agency for Research on Cancer, Lyon. 161–169. 1974.

2. 2. IARC Working Group on the Evaluation of the Carcinogenic Risk to Humans Furazolidone. In: IARC Monographs on the Evaluation of the Carcinogenic Risk to Humans, vol. 31, International Agency for Research on Cancer, Lyon. 1983.

3. 3. IARC Working Group on the Evaluation of the Carcinogenic Risk to Humans Nitrofural (nitrofurazone). In: IARC Monographs on the Evaluation of the Carcinogenic Risks of Chemicals to Humans, vol. 50, International Agency for Research on Cancer, Lyon. 195–209. 1990.

4. 4. IARC Working Group on the Evaluation of the Carcinogenic Risk to Humans. Nitrofurantoin. In: IARC Monographs on the Evaluation of the Carcinogenic Risks to Humans, vol. 50, International Agency for Research on Cancer, Lyon. 211–231. 1990.

5. 5. Zorzi RR, Jorge SD, Palace-Berl F, Pasqualoto KF, Bortolozzo LS, de Castro Siqueira AM, and Tavares LC. Exploring 5-nitrofuran derivatives against nosocomial pathogens: synthesis, antimicrobial activity and chemometric analysis. Bioorg Med Chem. 22: 2844–2854. 2014.

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