Inclusion of Nitrofurantoin into the Realm of Cancer Chemotherapy via Biology-Oriented Synthesis and Drug Repurposing

Author:

Elzahhar Perihan A.1ORCID,Nematalla Hisham A.2,Al-Koussa Houssam3,Abrahamian Carla4,El-Yazbi Amira F.5ORCID,Bodgi Larry67,Bou-Gharios Jolie67,Azzi Joyce67,Al Choboq Joelle67,Labib Hala F.8,Kheir Wassim Abou7ORCID,Abu-Serie Marwa M.9,Elrewiny Mohamed A.10,El-Yazbi Ahmed F.31011,Belal Ahmed S. F.1ORCID

Affiliation:

1. Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Alexandria University, Alexandria 21521, Egypt

2. Department of Pharmacology and Toxicology, Faculty of Pharmacy, Damanhour University, Damanhour 22516, Egypt

3. Department of Pharmacology and Toxicology, American University of Beirut, Beirut 11072020, Lebanon

4. Walther Straub Institute of Pharmacology and Toxicology, Faculty of Medicine, Ludwig-Maximilians-University, 80336 Munich, Germany

5. Department of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Alexandria University, Alexandria 21521, Egypt

6. Department of Radiation Oncology, American University of Beirut Medical Center, Beirut 11072020, Lebanon

7. Department of Anatomy, Cell Biology and Physiological Sciences, Faculty of Medicine, American University of Beirut, Beirut 11072020, Lebanon

8. Department of Pharmaceutical Chemistry, College of Pharmacy, Arab Academy of Science Technology and Maritime Transport, Alexandria 21913, Egypt

9. Medical Biotechnology Department, Genetic Engineering and Biotechnology Research Institute, City of Scientific Research and Technological Applications (SRTA-City), Alexandria 21934, Egypt

10. Faculty of Pharmacy and the Research and Innovation Hub, Alamein International University, Alamein 5060335, Egypt

11. Department of Pharmacology and Toxicology, Faculty of Pharmacy, Alexandria University, Alexandria 21521, Egypt

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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