Inclusion of Nitrofurantoin into the Realm of Cancer Chemotherapy via Biology-Oriented Synthesis and Drug Repurposing-Reference-Cited by-同舟云学术

Inclusion of Nitrofurantoin into the Realm of Cancer Chemotherapy via Biology-Oriented Synthesis and Drug Repurposing

Published:2023-03-15 Issue:7 Volume:66 Page:4565-4587
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Elzahhar Perihan A.¹^ORCID,Nematalla Hisham A.²,Al-Koussa Houssam³,Abrahamian Carla⁴,El-Yazbi Amira F.⁵^ORCID,Bodgi Larry⁶⁷,Bou-Gharios Jolie⁶⁷,Azzi Joyce⁶⁷,Al Choboq Joelle⁶⁷,Labib Hala F.⁸,Kheir Wassim Abou⁷^ORCID,Abu-Serie Marwa M.⁹,Elrewiny Mohamed A.¹⁰,El-Yazbi Ahmed F.³¹⁰¹¹,Belal Ahmed S. F.¹^ORCID

Affiliation:

1. Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Alexandria University, Alexandria 21521, Egypt

2. Department of Pharmacology and Toxicology, Faculty of Pharmacy, Damanhour University, Damanhour 22516, Egypt

3. Department of Pharmacology and Toxicology, American University of Beirut, Beirut 11072020, Lebanon

4. Walther Straub Institute of Pharmacology and Toxicology, Faculty of Medicine, Ludwig-Maximilians-University, 80336 Munich, Germany

5. Department of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Alexandria University, Alexandria 21521, Egypt

6. Department of Radiation Oncology, American University of Beirut Medical Center, Beirut 11072020, Lebanon

7. Department of Anatomy, Cell Biology and Physiological Sciences, Faculty of Medicine, American University of Beirut, Beirut 11072020, Lebanon

8. Department of Pharmaceutical Chemistry, College of Pharmacy, Arab Academy of Science Technology and Maritime Transport, Alexandria 21913, Egypt

9. Medical Biotechnology Department, Genetic Engineering and Biotechnology Research Institute, City of Scientific Research and Technological Applications (SRTA-City), Alexandria 21934, Egypt

10. Faculty of Pharmacy and the Research and Innovation Hub, Alamein International University, Alamein 5060335, Egypt

11. Department of Pharmacology and Toxicology, Faculty of Pharmacy, Alexandria University, Alexandria 21521, Egypt

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.2c01408

Reference64 articles.

1. Repurposing the Antihistamine Terfenadine for Antimicrobial Activity against Staphylococcus aureus

2. Transforming iodoquinol into broad spectrum anti-tumor leads: Repurposing to modulate redox homeostasis

3. An update on derivatisation and repurposing of clinical nitrofuran drugs

4. Drug repurposing in cancer

5. Drug repurposing: Iron in the fire for older drugs

Cited by 4 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Chromone-based small molecules for multistep shutdown of arachidonate pathway: Simultaneous inhibition of COX-2, 15-LOX and mPGES-1 enzymes;European Journal of Medicinal Chemistry;2024-02

2. Effect of bisphosphonates and statins on the in vitro radiosensitivity of breast cancer cell lines;Pharmacological Reports;2023-12-27

3. Synergistic integration of few-layer thick MXenes and small Pd nanocubes for enhanced electrochemical nitrofurantoin detection: Implications in pharmaceutical pollutant monitoring;Journal of Environmental Chemical Engineering;2023-12

4. New 2-alkoxycyanopyridine derivatives as inhibitors of EGFR, HER2, and DHFR: Synthesis, anticancer evaluation, and molecular modeling studies;Bioorganic Chemistry;2023-12