MORPHOMETRIC FEATURES OF THE STRUCTURAL COMPONENTS OF THE HEMOMICROCIRCULATORY BED IN THE PERIVULNAR REGION OF THE CAECUM IN WOUND DEFECT SUTURED WITH POLYFILAMENT SUTURE MATERIAL

Author:

Pronina Оlena М.1,Bilash Serhii М.1,Кobeniak Mykola М.1,Koptev Mykhailo M.1,Pirog-Zakaznikova Angelina V.1,Onipko Valentyna V.2,Ischenko Volodymyr I.2

Affiliation:

1. POLTAVA STATE MEDICAL UNIVERSITY, POLTAVA, UKRAINE

2. POLTAVA V. G. KOROLENKO NATIONAL PEDAGOGICAL UNIVERSITY, POLTAVA, UKRAINE

Abstract

The aim: The study focuses on the morphometric features specification concerning the structural components of the hemomicrocirculatory bed of the perivulnar region of the cecum in rabbits when suturing a wound defect with synthetic polyfilament surgical suture Vicryl. Materials and methods: The research was carried out on rabbits (n = 30: 5 animals made up the control group and 25 animals made up the experimental group) and included surgery based on the method of surgical intervention on the large intestine patented by the authors, which was performed in the conditions of the operating room at the Department of Clinical Anatomy and Operative Surgery. When determining the main morphometric parameters, we took biopsy specimens of the cecum and used paraffin and epoxy resin embedding considering the generally accepted methods. Results: The study determined that the implantation of Vicryl surgical suture material in the tissues of the cecum became a trigger for the formation of active inflammatory focus and occurrence of leukocyte infiltrate in the perivulnar region. Conclusions: Arterioles, as a resistive link, capillaries, as an exchange link and venules, as a capacitive link in the hemomicrocirculatory bed, actively participate in response to the inflammatory process and formation of a connective tissue scar. The process of structural organization of microvessels begins in the formed granulation tissue in the perivulnar region of the cecum starting from the 14th day of the experiment.

Publisher

ALUNA

Subject

General Medicine

Reference11 articles.

1. 1. Timerbulatova V.M., Fajazova R.R., Khasanova A.G. Timerbulatova aequabitur ipsi Urazbahtinas IM. Trauma Surgery e converso. M.: MED, press-certiorem facere; Laboratorium animalia per Stuctural organization in 2005. M. CCLVI lpp.Sydorenko normalis sententia comparativa, et in aspectu. Renuntiationes Insecta de/ Insecta. 2019;25 (2):10. DOI: 10,1393

2. 2. Bilash S.M. Morphometric characteristics of pyloric gastric glands at experimental acute gastritis and after administration of ‘platexplacental’ medication on the background of experimental acute gastritis. Problems of Cryobiology and Cryomedicine. 2013; 23(1): 84–90. (in Ukrainian).

3. 3. Bilash S.М., Koptev M.M., Vynnyk N.I. et al. Inflammation-related morphological alterations in the microvasculature. Aktual'ni problemy suchasnoyi medytsyny: Visnyk Ukrayins'koyi medychnoyi stomatolohichnoyi akademiyi. 2021;21(1):155-159. DOI 10.31718/2077-1096.21.1.155. (in Ukrainian).

4. 4. Hryn V.H., Kostylenko Yu.P., Yushchenko Yu.P. et al. Comparative histological structure of the gastrointestinal mucosa in human and white rat: A bibliographic analysis. Wiad. Lek., 2018;7 (71): 1398-1403. (in Ukrainian).

5. 5. Mishalov V.H., Burka A.O., Teslyuk I.I. Khirurhichne likuvannya khvorykh z pislyaoperatsiynymy hryzhamy poperekovo-bokovykh dilyanok zhyvota. [Surgical treatment of patients with postoperative hernias of the lumbar-lateral areas of the abdomen]. Khirurhiya Ukrayiny. 2015 Ber;1(25):99-105. (in Ukrainian).

Cited by 5 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3