Targeting tumors that lack methylthioadenosine phosphorylase (MTAP) activity
Author:
Publisher
Informa UK Limited
Subject
Cancer Research,Pharmacology,Oncology,Molecular Medicine
Link
http://www.tandfonline.com/doi/pdf/10.4161/cbt.11.7.14948
Reference50 articles.
1. Methylthioadenosine (MeSAdo) Phosphorylase Deficiency in Malignancy
2. A phase II multicenter study of L-alanosine, a potent inhibitor of adenine biosynthesis, in patients with MTAP-deficient cancer
3. Homozygous deletion of the MTAP gene in invasive adenocarcinoma of the pancreas and in periampullary cancer: A potential new target for therapy
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