A phase II multicenter study of L-alanosine, a potent inhibitor of adenine biosynthesis, in patients with MTAP-deficient cancer-Reference-Cited by-同舟云学术

A phase II multicenter study of L-alanosine, a potent inhibitor of adenine biosynthesis, in patients with MTAP-deficient cancer

Published:2008-07-11 Issue:1 Volume:27 Page:75-81
ISSN:0167-6997
Container-title:Investigational New Drugs
language:en
Short-container-title:Invest New Drugs

Author:

Kindler Hedy Lee,Burris Howard A.,Sandler Alan B.,Oliff Ira Anton

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology,Oncology

Link

http://link.springer.com/content/pdf/10.1007/s10637-008-9160-1.pdf

Reference27 articles.

1. Powell EL, Leoni LM, Canto MI et al (2005) Concordant loss of MTAP and p16/CDKN2A expression in gastroesophageal carcinogenesis: evidence of homozygous deletion in esophageal noninvasive precursor lesions and therapeutic implications. Am J Surg Pathol 29:1497–1504, doi: 10.1097/01.pas.0000170349.47680.e8

2. Illei PB, Rusch VW, Zakowski MF et al (2003) Homozygous deletion of CDKN2A and codeletion of the methylthioadenosine phosphorylase gene in the majority of pleural mesotheliomas. Clin Cancer Res 9:2108–2113

3. M’soka TJ, Nishioka J, Taga A et al (2000) Detection of methylthioadenosine phosphorylase (MTAP) and p16 gene deletion in T cell acute lymphoblastic leukemia by real-time quantitative PCR assay. Leukemia 14:935–940, doi: 10.1038/sj.leu.2401771

4. Schmid M, Malicki D, Nobori T et al (1998) Homozygous deletions of methylthioadenosine phosphorylase (MTAP) are more frequent than p16INK4A (CDKN2) homozygous deletions in primary non-small cell lung cancers (NSCLC). Oncogene 17:2669–2675, doi: 10.1038/sj.onc.1202205

5. Hori Y, Hori H, Yamada Y et al (1998) The methylthioadenosine phosphorylase gene is frequently co-deleted with the p16INK4a gene in acute type adult T-cell leukemia. Int J Cancer 75:51–56, doi: 10.1002/(SICI)1097-0215(19980105)75:1<51::AID-IJC9>3.0.CO;2-0

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