Comparison of Immunohistochemistry, Next-generation Sequencing and Fluorescence In Situ Hybridization for Detection of MTAP Loss in Pleural Mesothelioma

Author:

Febres-Aldana Christopher A.,Chang Jason C.,Jungbluth Achim A.,Adusumilli Prasad S.,Bodd Francis M.,Frosina Denise,Geronimo Jerica A.,Hernandez Enmily,Irawan Helen,Offin Michael D.,Rekhtman Natasha,Travis William D.,Vanderbilt Chad,Zauderer Marjorie G.,Zhang Yanming,Ladanyi Marc,Yang Soo-Ryum,Sauter Jennifer L.ORCID

Funder

Mesothelioma Applied Research Foundation

National Institutes of Health

U.S. Department of Defense

National Cancer Institute

Publisher

Elsevier BV

Reference39 articles.

1. WHO Classification of Tumours: Thoracic Tumours,2021

2. Homozygous deletion of CDKN2A and codeletion of the methylthioadenosine phosphorylase gene in the majority of pleural mesotheliomas;Illei;Clin Cancer Res,2003

3. Integrative molecular characterization of malignant pleural mesothelioma;Hmeljak;Cancer Discov,2018

4. Comprehensive genomic analysis of malignant pleural mesothelioma identifies recurrent mutations, gene fusions and splicing alterations;Bueno;Nat Genet,2016

5. Immunohistochemical detection of MTAP and BAP1 protein loss for mesothelioma diagnosis: comparison with 9p21 FISH and BAP1 immunohistochemistry;Hida;Lung Cancer,2017

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