IDO inhibits a tryptophan sufficiency signal that stimulates mTOR: A novel IDO effector pathway targeted by D-1-methyl-tryptophan-Reference-Cited by-同舟云学术

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IDO inhibits a tryptophan sufficiency signal that stimulates mTOR: A novel IDO effector pathway targeted by D-1-methyl-tryptophan

Published:2012-12 Issue:9 Volume:1 Page:1460-1468
ISSN:2162-402X
Container-title:OncoImmunology
language:en
Short-container-title:OncoImmunology

Author:

Metz Richard,Rust Sonja,DuHadaway James B.,Mautino Mario R.,Munn David H.,Vahanian Nicholas N.,Link Charles J.,Prendergast George C.

Publisher

Informa UK Limited

Subject

Oncology,Immunology,Immunology and Allergy

Link

http://www.tandfonline.com/doi/pdf/10.4161/onci.21716

Reference36 articles.

1. Towards a genetic definition of cancer-associated inflammation: role of the IDO pathway;Prendergast;Am J Pathol,2010

2. Immune escape as a fundamental trait of cancer: focus on IDO;Prendergast;Oncogene,2008

3. IDO is a nodal pathogenic driver of lung cancer and metastasis development;Smith;Cancer Discov,2012

4. Physiologic control of the functional status of Foxp3+ regulatory T cells;Mellor;J Immunol,2011

5. Chronic inflammation that facilitates tumor progression creates local immune suppression by inducing indoleamine 2,3 dioxygenase;Muller;Proc Natl Acad Sci U S A,2008

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