Trogocytosis generates acquired regulatory T cells adding further complexity to the dysfunctional immune response in multiple myeloma
Author:
Publisher
Informa UK Limited
Subject
Oncology,Immunology,Immunology and Allergy
Link
http://www.tandfonline.com/doi/pdf/10.4161/onci.22032
Reference10 articles.
1. CD86+ or HLA-G+ can be transferred via trogocytosis from myeloma cells to T cells and are associated with poor prognosis
2. Tregs and rethinking cancer immunotherapy
3. Clonal expansions of cytotoxic T cells exist in the blood of patients with Waldenström macroglobulinemia but exhibit anergic properties and are eliminated by nucleoside analogue therapy
4. T-cell expansions in patients with multiple myeloma have a phenotype of cytotoxic T cells
5. Prognostically significant cytotoxic T cell clones are stimulated after thalidomide therapy in patients with multiple myeloma
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1. Good Cop, Bad Cop: Profiling the Immune Landscape in Multiple Myeloma;Biomolecules;2023-11-07
2. Inappropriate Expression of PD-1 and CTLA-4 Checkpoints in Myeloma Patients Is More Pronounced at Diagnosis: Implications for Time to Progression and Response to Therapeutic Checkpoint Inhibitors;International Journal of Molecular Sciences;2023-03-17
3. The Leading Role of the Immune Microenvironment in Multiple Myeloma: A New Target with a Great Prognostic and Clinical Value;Journal of Clinical Medicine;2022-04-29
4. When killers become thieves: Trogocytosed PD-1 inhibits NK cells in cancer;Science Advances;2022-04-15
5. Deciphering mechanisms of immune escape to inform immunotherapeutic strategies in multiple myeloma;Journal of Hematology & Oncology;2022-02-16
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