Novel one pot synthesis of curcumin quantum dots for non-enzymatic highly sensitive and selective detection of dopamine

Abstract

This is the first report on the exploration of the electrocatalytic performance of curcumin quantum dots synthesized by a novel method for nonenzymatic, highly sensitive and selective detection of dopamine. The study was carried out in the presence of high concentrations of its potential neurological interferents having similar oxidation potential to represent real physiological conditions. This proposed novel sensor showed good sensitivity of 14.28 µA nM-1 cm-2 in the linear range of 0.05 nM to 1 nM, with very low detection limit (0.002 nM) and quantification limit (0.006 nM), which has not been attained by other sensing systems so far.