Affiliation:
1. Veltischev Research and Clinical Institute for Pediatrics, Pirogov Russian National Research Medical University; Russian Medical Academy of Continuous Professional Education; Morozov Children’s Municipal Clinical Hospital
2. Pavlov First Saint-Petersburg State Medical University
3. Rostov State Medical University
Abstract
Personalized management of children with chronic inflammatory non-communicable diseases, including bronchial asthma, have been extremely elaborated last decade. Highly informative biomarkers exploring is one of important conditions of this management. Testing aim, molecule’s pathogeneticrole, adequate biomaterial choice and test validity determine possibility and effectiveness of biomarker application. The paper represents key features of most perspective asthma biomarkers and discuss advantages and disadvantages of their using in pediatric practice. with rational biomarkers implementation nowadays one can separate patients with asthma development risk, provide a rational prevention, confirm the diagnosis and evaluate severity in some cases, optimize anti-inflammatory treatment, prognose the treatment response, evaluate future exacerbation probability, devote children with severe asthma in-time to initiate and conduct biological therapy for them.
Publisher
Rostov State Medical University
Subject
General Earth and Planetary Sciences,General Environmental Science
Reference63 articles.
1. König I.R, Fuchs O., Hansen G., von Mutius E., Kopp M.V. What is precision medicine? Eur. Respir J. 2017; 50(4):1700391. DOI: 10.1183/13993003.00391-2017
2. Pampura A. N. Development of pediatric allergology: Problems and prospects. Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics). 2015. – Vol. 60. – No. 1. – pp. 7-15. (In Russ.). eLIBRARY ID: 23093968
3. Bousquet J., Hellings P.W., Agache I., Bedbrook A, Bachert C. et al. ARIA 2016: Care pathways implementing emerging technologies for predictive medicine in rhinitis and asthma across the life cycle. Clin Transl Allergy. 2016; 30(6):47.
4. DOI: 10.1186/s13601-016-0137-4.
5. Raulf-Heimsoth, M., Wirtz, C., Papenfuss, F., Baur, X. Nasal lavage mediator profile and cellular composition of nasal brushing material during latex challenge tests. Clinical and experimental allergy: journal of the British Society for Allergy and Clinical Immunology. 2000; 30(1):110-121. doi:10.1046/j.1365-2222.2000.00690.x
Cited by
1 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献