Affiliation:
1. Veltischev Research and Clinical Institute for Pediatrics, Pirogov Russian National Research Medical University; Russian Medical Academy of Continuous Professional Education; Morozov Children’s Municipal Clinical Hospital
2. Pavlov First Saint-Petersburg State Medical University
3. Rostov State Medical University
Abstract
Personalized management of children with chronic inflammatory non-communicable diseases, including bronchial asthma, have been extremely elaborated last decade. Highly informative biomarkers exploring is one of important conditions of this management. Testing aim, molecule’s pathogeneticrole, adequate biomaterial choice and test validity determine possibility and effectiveness of biomarker application. The paper represents key features of most perspective asthma biomarkers and discuss advantages and disadvantages of their using in pediatric practice. with rational biomarkers implementation nowadays one can separate patients with asthma development risk, provide a rational prevention, confirm the diagnosis and evaluate severity in some cases, optimize anti-inflammatory treatment, prognose the treatment response, evaluate future exacerbation probability, devote children with severe asthma in-time to initiate and conduct biological therapy for them.
Publisher
Rostov State Medical University
Subject
General Earth and Planetary Sciences,General Environmental Science
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