The impact of statins on the course of a new coronavirus infection: myth or reality?

Abstract

The review presents data regarding the non-lipid effects of statins that may be useful in the treatment of patients with new coronavirus infection. The effects of statins such as antiflammatory, immunomodulatory, antithrombotic, as well as the restoration of endothelial dysfunction and the normalization of fibrinolysis are discussed. The effect of statins on SARS-CoV2 entry into the cell and viral replication is discussed. Recent data from observational clinical studies on the effect of statins on the severity of the course of a new coronavirus infection are presented.