Liver microsomal lipid enhances the activity and redox coupling of colocalized cytochrome P450 reductase-cytochrome P450 3A4 in nanodiscs-Reference-Cited by-同舟云学术

Liver microsomal lipid enhances the activity and redox coupling of colocalized cytochrome P450 reductase-cytochrome P450 3A4 in nanodiscs

Published:2017-06-30 Issue:14 Volume:284 Page:2302-2319
ISSN:1742-464X
Container-title:The FEBS Journal
language:en
Short-container-title:FEBS J

Author:

Liu Kang-Cheng¹,Hughes John M. X.¹,Hay Sam¹,Scrutton Nigel S.¹

Affiliation:

1. Centre for Synthetic Biology of Fine and Speciality Chemicals (SYNBIOCHEM); School of Chemistry; Manchester Institute of Biotechnology; The University of Manchester; UK

Funder

EPSRC/BBSRC Synthetic Biology Research Centre SYNBIOCHEM

Publisher

Wiley

Subject

Cell Biology,Molecular Biology,Biochemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/febs.14129/fullpdf

Reference70 articles.

1. Cytochromes P450 and metabolism of xenobiotics;Anzenbacher;Cell Mol Life Sci,2001

2. Cytochrome P450 enzymes in drug metabolism: regulation of gene expression, enzyme activities, and impact of genetic variation;Zanger;Pharmacol Ther,2013

3. Survey of human oxidoreductases and cytochrome P450 enzymes involved in the metabolism of xenobiotic and natural chemicals;Rendic;Chem Res Toxicol,2015

4. Mechanism of oxidation reactions catalyzed by cytochrome P450 enzymes;Meunier;Chem Rev,2004

5. Mechanisms of cytochrome P450 substrate oxidation: minireview;Guengerich;J Biochem Mol Toxicol,2007

Cited by 14 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Replacing animal-derived components in in vitro test guidelines OECD 455 and 487;Science of The Total Environment;2023-04

2. Non-Ionic Inulin-Based Polymer Nanodiscs Enable Functional Reconstitution of a Redox Complex Composed of Oppositely Charged CYP450 and CPR in a Lipid Bilayer Membrane;Analytical Chemistry;2022-08-17

3. Nanodiscs: A toolkit for membrane protein science;Protein Science;2020-11-16

4. Human Liver Microsomes Immobilized on Magnetizable Beads: A Novel Approach to Study In Vitro Drug Metabolism;Drug Metabolism and Disposition;2020-05-30

5. How Oxidative Systems Metabolise Substrates;Human Drug Metabolism;2020-02-21