Structure of the adenylation domain Thr1 involved in the biosynthesis of 4-chlorothreonine in Streptomyces sp. OH-5093-protein flexibility and molecular bases of substrate specificity-Reference-Cited by-同舟云学术

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Structure of the adenylation domain Thr1 involved in the biosynthesis of 4-chlorothreonine in Streptomyces sp. OH-5093-protein flexibility and molecular bases of substrate specificity

Published:2017-08-07 Issue:18 Volume:284 Page:2981-2999
ISSN:1742-464X
Container-title:The FEBS Journal
language:en
Short-container-title:FEBS J

Author:

Scaglione Antonella¹²,Fullone Maria Rosaria³,Montemiglio Linda Celeste¹³,Parisi Giacomo¹²,Zamparelli Carlotta³,Vallone Beatrice¹³,Savino Carmelinda²,Grgurina Ingeborg³

Affiliation:

1. Department of Biochemical Sciences “A. Rossi Fanelli”; Istituto Pasteur-Fondazione Cenci Bolognetti; Sapienza University of Rome; Italy

2. Institute of Molecular Biology and Pathology; CNR - National Research Council of Italy; Rome Italy

3. Department of Biochemical Sciences “A. Rossi Fanelli”; Sapienza University of Rome; Italy

Funder

Sapienza Università di Roma

Consiglio Nazionale delle Ricerche

Regione Lazio

Publisher

Wiley

Subject

Cell Biology,Molecular Biology,Biochemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/febs.14163/fullpdf

Reference57 articles.

1. Nonribosomal peptide synthetases involved in the production of medically relevant natural products;Felnagle;Mol Pharm,2008

2. Molecular mechanisms underlying nonribosomal peptide synthesis: approaches to new antibiotics;Sieber;Chem Rev,2005

3. Assembly-line enzymology for polyketide and nonribosomal peptide antibiotics: logic, machinery, and mechanisms;Fischbach;Chem Rev,2006

4. Structures of five components of the actinomycin Z complex from Streptomyces fradiae, two of which contain 4-chlorothreonine;Lackner;J Nat Prod,2000

5. The structure of syringomycins A1, E and G;Segre;FEBS Lett,1998

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3. Structural, biochemical and bioinformatic analyses of nonribosomal peptide synthetase adenylation domains;Natural Product Reports;2024

4. Structural advances toward understanding the catalytic activity and conformational dynamics of modular nonribosomal peptide synthetases;Natural Product Reports;2023

5. Recent advances in the structural analysis of adenylation domains in natural product biosynthesis;Current Opinion in Chemical Biology;2022-12

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